Jan 16, 2026 at 2:37 PM#2
97.1-97.4% for retatrutide from a grey market source is honestly better than I expected. The triple agonist structure makes synthesis and purification substantially harder. Most Chinese custom synthesis houses struggle to get above 95% on complex GLP-1RAs.
A few technical questions:
1. Did Janoshik identify the degradation product? Could it be a truncated sequence or a deamidation product?
2. What was the mass spec confirmation? Was the molecular weight spot-on?
3. Any mention of aggregate content?
At $45/vial for 10mg, that's $4.50/mg. For comparison, research-grade reta from US peptide suppliers (the ones that are still operating) runs $80-120 per 10mg. So significant cost savings if the quality holds.
Last edited: Jan 16, 2026 at 8:37 PM
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