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ForumsNutrition & SupplementationVitamin D optimization on GLP-1 — need advice

Vitamin D optimization on GLP-1 — need advice

KetoKyle Tue, Dec 9, 2025 at 12:44 AM 10 replies 1,000 viewsPage 1 of 2
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KetoKyle
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Jul 2024
Utah
Dec 9, 2025 at 12:44 AM#1

I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

The narrow version of the question is which deficiencies actually show up when intake drops this far, and which are worth testing rather than supplementing blind.

I have searched first, so if this is covered somewhere point me at it and I will read it.

42 12laura_annarbor, JenMemphis, pat_auckland and 39 others
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Dr.NutriCornell
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Mar 2024
Ithaca, NY
Dec 9, 2025 at 12:55 AM#2
KetoKyle said:
I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Vitamin and mineral labs to check while on micronutrients — my doctor orders these quarterly:

  • B12: Can drop due to reduced GI absorption. Mine went from 650 to 380 — now supplementing.
  • Iron/Ferritin: Reduced food intake = reduced iron. Ferritin dropped from 70 to 27. Supplementing.
  • Vitamin D: Was already low (25 ng/mL), now taking 5000 IU daily.
  • Folate: Stable, no issues.
  • Zinc: Slightly low, added a multivitamin with zinc.

Nutritional deficiencies are a real risk when you're eating significantly less. Don't skip your labs!

41 11Dr.SleepRoch, laura_annarbor, JenMemphis and 38 others
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LabKate
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Jan 2024
Oregon
Dec 9, 2025 at 1:06 AM#3
Dr.NutriCornell said:
Vitamin and mineral labs to check while on micronutrients — my doctor orders these quarterly: B12: Can drop due to reduced GI absorption.

Iron studies on micronutrients — important especially for women:

MarkerBaselineMonth 6After Supplementation
Ferritin692754
Iron995987
TIBC319389339
Transferrin Sat33%19%28%

My ferritin cratered at month 6 from reduced dietary intake. Iron bisglycinate 36mg with vitamin C brought it back up. Don't wait for anemia symptoms — test proactively.

40 10Dr.SleepRoch, laura_annarbor, JenMemphis and 37 others
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Dr.NephBHM_UK
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Jun 2024
Birmingham, UK
Dec 9, 2025 at 1:17 AM#4
KetoKyle said:
I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Adding a me-too, because a thread of one person's experience is not much use.

39 9SurmountFan_IN, PeptideChemSF, A1cHero_PHX and 36 others
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claudia_zurich
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Zurich, CH
Dec 9, 2025 at 2:16 AM#5

Clinical perspective, offered as context rather than as advice.

Vitamin D levels and micronutrients: an often-overlooked connection. Obese individuals store vitamin D in adipose tissue, making it less bioavailable. As you lose fat, vitamin D can actually increase WITHOUT supplementation.

My trajectory: Baseline 18 ng/mL → Month 6 (with supplement) 42 ng/mL → Month 12 48 ng/mL. Target is 40-60 ng/mL. Adequate vitamin D supports immune function, bone health, and mood — all relevant during weight loss.

Last edited: Dec 9, 2025 at 8:16 AM
38 8kevin_tulsa, Dr.PainCLE, mike_mealprep and 35 others
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