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ForumsNutrition & SupplementationFiber supplementation for GLP-1 constipation — 12 month update Page 2

Fiber supplementation for GLP-1 constipation — 12 month update

claudia_zurich Tue, Jul 29, 2025 at 4:19 PM 7 replies 1,316 viewsPage 2 of 2
anders_CPH
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Jul 29, 2025 at 10:12 PM#6
julia.endo said:
The mechanism is slowed transit plus reduced intake, and that combination determines which interventions work.

Worth saying plainly that not all of this is benign. Severe constipation on delayed gastric emptying has produced obstruction and ileus cases, rarely but genuinely. Pain with vomiting and no bowel movement is not a fiber conversation.

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DataDave
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Jul 30, 2025 at 12:31 AM#7
claudia_zurich said:
Constipation replaced nausea at around week five and has been the more persistent of the two by a wide margin.

Gastroparesis symptoms with constipation: the delayed gastric emptying from GLP-1 agonists can cause early satiety, bloating, and feeling "full" for hours after a small meal.

Tips: eat your protein FIRST (most important macro), then vegetables, then carbs last. Chew thoroughly — 20-30 chews per bite isn't excessive. Avoid carbonated beverages with meals. If symptoms are severe, your doctor may recommend a gastric emptying study.

Last edited: Jul 30, 2025 at 1:31 AM
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EndoResFellow
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Jul 30, 2025 at 2:50 AM#8
anders_CPH said:
Worth saying plainly that not all of this is benign.

Acid reflux and constipation: I developed GERD symptoms around week 7 that I'd never had before. The delayed gastric emptying means food and acid sit in your stomach longer.

Management that works for me: elevate head of bed 6 inches, don't eat within 3 hours of lying down, avoid trigger foods (tomato, citrus, spicy, chocolate), and famotidine 20mg at bedtime. Much better now.

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MaxMetOK
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Jul 30, 2025 at 5:09 AM#9

A narrower follow-up, since the general answer is now clear:

What the mechanism is, because if it is transit rather than water then fiber is the wrong lever?

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claudia_zurich
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Jul 30, 2025 at 4:16 PM#10

Reporting back.

Update — the osmotic agent was the thing. I had been reaching for a stimulant, which was making the next day worse.

Last edited: Jul 30, 2025 at 10:16 PM
46 19kevin_tulsa, Dr.PainCLE, mike_mealprep and 43 others
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