From the other side of the consultation, briefly. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

quinn_sf said:

Two things anyone can check: a state licence number for a 503A, and an FDA outsourcing-facility registration for a 503B.

Bookmarking. The distinction being drawn above is the one nobody else makes. I will report back once I have actually tried it.

Clinical perspective, offered as context rather than as advice. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

NurseLeah_Nash said:

Worth answering the question that was asked rather than the one behind it.

Same position here, arrived at the long way round. Steady state is the thing most people miss. The terminal half-life is about a week, so every dose step takes four to five weeks to fully express itself. Judging a step at day ten is judging the ascent, not the plateau, and it is the single commonest reason people escalate before they needed to.

Worth separating that from compounded supply, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.