Closing the loop on my own question.
Update: the thing I was blaming turned out not to be the cause. Leaving the original post as written rather than editing it, so the mistake stays visible for whoever searches this next.
One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
A narrower follow-up, since the general answer is now clear:
What did you change at the same time, and can you separate the two now?
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Browse GL Biochemquinn_sf said:If you are going to change something, change one thing and give it long enough to express itself.
Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.
quinn_sf said:If you are going to change something, change one thing and give it long enough to express itself.
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.