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ForumsDosing & ProtocolsMicro-dosing semaglutide — 12 month update Page 2

Micro-dosing semaglutide — 12 month update

FDA_TrackerJim Fri, Apr 17, 2026 at 10:57 AM 17 replies 874 viewsPage 2 of 4
claudia_zurich
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Apr 17, 2026 at 12:11 PM#6

Quick practical note — if you're doing 0.125mg from a compounded vial, the reconstitution math matters a lot here. With a 5mg vial:

  • Add 2mL BAC water → 2.5mg/mL → 0.125mg = 0.05mL = 5 units

5 units on an insulin syringe is a very small amount — just be sure you're using a syringe with fine enough markings. A 0.3mL (30-unit) syringe will have individual unit markings and be much easier to read accurately at this volume than a full 1mL syringe.

30 0emma_london, tammy_FL, Dr.LipidDallas and 27 others
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VanRx_Mike
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Apr 17, 2026 at 12:39 PM#7

Great call on the syringe. I'll order the 0.3mL ones. Thank you for the advice! 🙏

Last edited: Apr 17, 2026 at 3:39 PM
29 24MikeNYC_runner and 26 others
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Admin
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Apr 17, 2026 at 1:07 PM#8

Good discussion. I'll just add the standard disclaimer that micro-dosing is off-label and should be done under provider supervision. We don't want anyone reading this thread and deciding to start at a random low dose without medical guidance. Your provider can factor in your full medical history, not just your weight.

28 23RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 25 others
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