Dr.LipidDallas said:Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…
Genuinely useful, thank you. I had the facts and not the framework.
Adding the clinical framing, because it changes how the question reads. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.
Dr.BariatricHTX said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.
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Browse GL BiochemOne concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
Moderator note: the sourcing question belongs in the vendor section and has been split out. Tagging this one for the weekly digest.