Reporting back.

Update — I was wrong in the opening post, specifically about the direction. Correcting it here rather than editing it away.

Dr.GutHealth said:

Practical: whatever you change, write down the date and the reason.

There is a second half to this that has not been said yet. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

Coming back to something from earlier in the thread, because it keeps being talked past:

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

Following on from Dr.GutHealth — and this may be the naive question:

Was that from a primary source or from a summary of one?

Dr.EndoEP said:

The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.