Dr.DermMIA said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.
Dr.LeslieOBGYN said:The pharmacokinetics explain nearly every practical question asked here.
Thank you for spelling out the reasoning rather than just the conclusion. Sending this to two other people who asked me the same thing last week.
Dr.DermMIA said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
This is where I part company with the consensus forming above. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.
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Browse GL BiochemThe figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
I would rather be corrected than agreed with, if it comes to it.