Adding the clinical framing, because it changes how the question reads. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

Dr.AddMedPHL said:

If you are going to change something, change one thing and give it long enough to express itself.

There is a second half to this that has not been said yet. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

Adding the numbers, since they settle part of this. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

Following on from Dr.AddMedPHL — and this may be the naive question:

Was that from a primary source or from a summary of one?

Moderator note: a couple of off-topic posts removed. Carry on.