RunnerRach said:

Reporting back with a partial result, because a partial result is still better than silence.

Pushing back on RunnerRach here. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

Happy to go further on any of that.

RunnerRach said:

Reporting back with a partial result, because a partial result is still better than silence.

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

RunnerRach said:

Reporting back with a partial result, because a partial result is still better than silence.

This is exactly what I could not find anywhere else. Printing the relevant bit and taking it with me.

From the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

paige_pharma said:

The mechanism and the magnitude are separate questions.

Mine went the same way, slower.