Dr.SleepRoch said:The trials generally allowed a step to be held or reduced and then retried, and people who did that mostly arrived at the same place a few weeks…
Bookmarking. The distinction being drawn above is the one nobody else makes.
Clinical perspective, offered as context rather than as advice. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.
Dr.NutriCornell said:Dose escalation anxiety for titration: I was terrified to move from 0.5mg to 1.0mg based on horror stories in this forum.
I read this differently from Dr.NutriCornell, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
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Browse GL BiochemThe figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
Happy to go further on any of that.
Moderator note: a couple of off-topic posts removed. Thread quality here is what the rules are for. Keep it up.