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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOff-TopicThrift store transformation — before/after outfit edition Page 3

Thrift store transformation — before/after outfit edition

WendyG_ATL Sun, May 31, 2026 at 10:13 PM 17 replies 438 viewsPage 3 of 4
labquiet_amy
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Jun 2, 2026 at 7:34 AM#11
andrew_nyc said:
The GLP-1 and alcohol use disorder connection, relevant to food noise: observational data from Scandinavian registries shows reduced alcohol-related…

Rebound hunger after missed dose of food noise: I missed my injection by 3 days due to a shipping delay and the hunger came ROARING back. Like a switch flipped. It was eye-opening to feel the difference.

This experience actually reinforced my understanding of what the medication does — it's not just "suppressing appetite," it's normalizing dysregulated hunger signaling. When the drug wears off, you feel the full force of what it was managing.

Last edited: Jun 2, 2026 at 9:34 AM
5 3TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 2 others
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DerekSJ_a1c
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Jun 2, 2026 at 4:30 PM#12
jason_sac26 said:
Neuroscience perspective on food noise: GLP-1 receptors are expressed throughout the CNS, with high density in the hypothalamic arcuate nucleus, area…

Thank you — that is the clearest version of this I have read, and I have read a lot of them.

6 4Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 3 others
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marcus_mpls
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Jun 3, 2026 at 1:26 AM#13
andrew_nyc said:
The GLP-1 and alcohol use disorder connection, relevant to food noise: observational data from Scandinavian registries shows reduced alcohol-related…

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

7 5tane_welly, Dr.PathRoch, mona_PHX and 4 others
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FDA_TrackerJim
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Jun 3, 2026 at 10:22 AM#14

One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

8 6Dr.LeslieOBGYN, MikeNYC_runner and 5 others
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mike_mod
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Jun 3, 2026 at 7:19 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. No action needed from anybody.

9 7PurityPaulOR, MaxMetOK, MounjBrad and 6 others
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