Dr.PainCLE said:The mechanism is more central than most summaries suggest.
Saving this. It is the first explanation that did not require me to already understand it. Printing the relevant bit and taking it with me.
Clinical perspective, offered as context rather than as advice. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
Correct me if the detail matters more than I have assumed.
Dr.LeslieOBGYN said:Start from the measurement rather than the conclusion.
This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.
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Browse GL BiochemThe figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.
Ask again with the specifics and you will get a better answer than this one.