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ForumsPharmacology & MechanismsIncretin effect in healthy vs T2DM — 12 month update Page 3

Incretin effect in healthy vs T2DM — 12 month update

marco_milano Mon, Oct 20, 2025 at 2:49 AM 28 replies 1,548 viewsPage 3 of 6
BariatricNurseD
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Oct 21, 2025 at 10:50 AM#11
Dr.EM_Chicago said:
Patient selection optimization for glycaemic control: emerging predictive biomarkers for GLP-1 agonist response include: Biomarker Association…

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

Last edited: Oct 21, 2025 at 3:50 PM
22 20tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 19 others
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oliver_london
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Oct 22, 2025 at 3:13 AM#12
roxy_nash said:
Insulin sensitivity test (HOMA-IR) on glycaemic control — arguably the most important metabolic marker most people aren't tracking: HOMA-IR = (fasting…

That reframing is the part I needed.

23 21MikeNYC_runner and 20 others
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Dr.PulmRoch
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Oct 22, 2025 at 7:36 PM#13
Dr.EM_Chicago said:
Patient selection optimization for glycaemic control: emerging predictive biomarkers for GLP-1 agonist response include: Biomarker Association…

This is where I part company with the consensus forming above. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

24 22AttorneyGrant, DebRD_ATL, KristenIndy and 21 others
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LabKate
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Oct 23, 2025 at 11:59 AM#14

One concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

25 23emily_PDX, Dr.SleepRoch, laura_annarbor and 22 others
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Admin
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Oct 24, 2025 at 4:21 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Report rather than reply if it drifts again.

26 24PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 23 others
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