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ForumsDosing & ProtocolsMath is hard - help me with reconstitution please — May 2025 Page 2

Math is hard - help me with reconstitution please — May 2025

TrialTracker_MD Thu, May 16, 2024 at 7:05 AM 10 replies 2,033 viewsPage 2 of 2
Dr.MetabolicMD
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Jan 2024
Rochester, MN
May 17, 2024 at 3:05 AM#6
LipidDoc_ATL said:
Dead space is the answer to the missing dose.

I am going to disagree with reconstituting low as a general rule. More diluent, more punctures, more in-use days at room temperature, and the stability trade-off is real. Precision is not the only variable being optimised.

2 22SleepDoc_PDX, RegAffairsDC
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wendy_avl
Member
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Oct 2024
Asheville, NC
May 17, 2024 at 11:03 AM#7
TrialTracker_MD said:
I reconstituted a 10mg vial with 2ml of bacteriostatic water and I want someone to check my unit arithmetic before I draw anything, because I keep…

Ongoing cost tracking for dosing arithmetic — transparency for the community:

Monthly medication cost: $157
Supplies (syringes, BAC water, alcohol swabs): ~$10/month
Janoshik testing: ~$12/month (amortized quarterly)
Lab work: ~$47/month (amortized quarterly)
Total: ~$217/month

Compare to brand Wegovy at $1247/month without insurance. Compounded is roughly 85% cheaper for what I have found to be clinically equivalent medication.

Last edited: May 17, 2024 at 5:03 PM
1 21DoseLogDan
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claudia_zurich
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Jul 2024
Zurich, CH
May 17, 2024 at 7:01 PM#8
Dr.MetabolicMD said:
I am going to disagree with reconstituting low as a general rule.

Just received my dosing arithmetic order — packaging review:

  • Outer box: plain brown, no medication identifiers (discreet) ✅
  • Inner insulation: Styrofoam with 3 gel ice packs ✅
  • Temperature: vials were cold to touch on arrival ✅
  • Labeling: lot number, BUD, compound name, concentration ✅
  • Included: COA, reconstitution instructions, dosing card ✅

This is what professional compounding pharmacy shipping looks like. If your order arrives without these basics, reconsider your vendor.

50 20Dr.LipidDallas, alex_tucson, kevin_tulsa and 47 others
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wanda_boise
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Aug 2024
Boise, ID
May 18, 2024 at 2:59 AM#9

One thing that is still open after Dr.NephBHM_UK’s answer:

How to check the arithmetic without trusting a website calculator, since three calculators gave me three answers?

Last edited: May 18, 2024 at 7:59 AM
49 19nick_SD_fit, ben_calgary, patPC_UT and 46 others
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TrialTracker_MD
Senior Member
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Jan 2024
Maryland
May 19, 2024 at 5:14 PM#10

OP back with an update, since a thread like this is useless without one.

Follow-up: it was dead space. Switching to a low-dead-space fixed-needle syringe gave me the tenth dose back.

35 8lori_vegas, Dr.PulmRoch, maya_sedona and 32 others
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