mike_nyc said:Start from the measurement rather than the conclusion.
No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.
OP back with an update, since a thread like this is useless without one.
For the archive: it took about six weeks rather than the two I expected, and the difference between those two numbers was the whole of my problem.
Clinical perspective, offered as context rather than as advice. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
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Browse GL BiochemTrialNerd_Beth said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
Second this. The detail I would add is minor and it is already implied above.
TrialNerd_Beth said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
There is a second half to this that has not been said yet. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.