claudia_zurich said:

Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

wei_SG said:

Agreed, with a caveat about community reputation: it is a lagging indicator.

Thank you for spelling out the reasoning rather than just the conclusion. Sending this to two other people who asked me the same thing last week.

claudia_zurich said:

Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Correct me if the detail matters more than I have assumed.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.