Dr.NephBHM_UK said:

Peptide calculator app recommendation for dosing arithmetic: I use ReconCalc to calculate reconstitution volumes and injection doses.

Sharing my dosing arithmetic titration experience with compounded semaglutide — I have been tracking injection volumes meticulously:

Using 5mg/2mL concentration with 1cc insulin syringes:

• Month 1: 10 units (0.25mg) — mild appetite reduction
• Month 2: 20 units (0.5mg) — significant appetite suppression
• Month 3: 30 units (0.75mg) — custom intermediate dose
• Month 4: 40 units (1.0mg) — optimal for me, staying here

The beauty of compounded vials is you can do custom intermediate doses. My provider was great about tailoring to my response.

Dr.EM_Chicago said:

The arithmetic is right and one caveat matters: a U-40 syringe changes the markings, not the volumes.

Saving this. It is the first explanation that did not require me to already understand it. I will report back once I have actually tried it.

Dr.NephBHM_UK said:

Peptide calculator app recommendation for dosing arithmetic: I use ReconCalc to calculate reconstitution volumes and injection doses.

For anyone reconstituting dosing arithmetic peptides: the water-to-powder ratio determines your concentration. Here's my reference:

More water = easier to measure small doses but vial runs out faster. Find the balance that works for your dose.

PharmD_Rodriguez said:

I reconstituted a 10mg vial with 2ml of bacteriostatic water and I want someone to check my unit arithmetic before I draw anything, because I keep…

Comparison of compounded dosing arithmetic delivery formats I've tried:

I use lyophilized vials for cost and stability. The reconstitution takes 30 seconds once you've done it a few times.

Moderator note: the sourcing question belongs in the vendor section and has been split out. Carry on.