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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsCan someone explain how this drug works like I am not a scientist — what worked for you? Page 3

Can someone explain how this drug works like I am not a scientist — what worked for you?

DebRD_ATL Sat, Feb 22, 2025 at 11:54 AM 16 replies 1,786 viewsPage 3 of 4
MikeFit_NJ
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Feb 24, 2025 at 9:11 PM#11
Dr.BariatricHTX said:
Amycretin (AMY/GLP-1 dual agonist) emerging data relevant to the pharmacology: Phase 1 showed -13.1% body weight at only 12 weeks, the fastest…

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

44 17LeilaHI, marcus_mpls, DeniseRN_TPA and 41 others
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GenomicsKate
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Feb 26, 2025 at 8:47 AM#12
DerekSJ_a1c said:
The mechanism is more central than most summaries suggest.

That reframing is the part I needed. I will report back once I have actually tried it.

45 18KristenIndy, MarkLI_maint, Dr.PeteFamMed and 42 others
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patPC_UT
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Feb 27, 2025 at 8:22 PM#13
Dr.BariatricHTX said:
Amycretin (AMY/GLP-1 dual agonist) emerging data relevant to the pharmacology: Phase 1 showed -13.1% body weight at only 12 weeks, the fastest…

Pushing back on Dr.BariatricHTX here. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

Last edited: Feb 28, 2025 at 1:22 AM
46 19TomFromTexas, mike.trainer_LA, sarah_nash92 and 43 others
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hank_denver
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Mar 1, 2025 at 7:56 AM#14

The figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

47 20fiona_VT, denise_HTX, raj_cambridge and 44 others
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Admin
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Mar 2, 2025 at 7:29 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.

Last edited: Mar 2, 2025 at 11:29 PM
48 21PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 45 others
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