The figures, for anyone assembling their own picture. Because it is glucose-dependent, this class carries a low intrinsic hypoglycaemia risk on its own — the risk arrives when it is combined with insulin or a sulfonylurea, which usually need reducing.
Following on from sophie_paris — and this may be the naive question:
Why A1C lags the way it does, and what to look at in the meantime if you want to know sooner?
bri_stats said:Because it is glucose-dependent, this class carries a low intrinsic hypoglycaemia risk on its own — the risk arrives when it is combined with insulin…
Coming at bri_stats’s question from a different direction. HbA1c reflects roughly three months of average glycaemia weighted toward the most recent weeks, which is why repeating it at six weeks tells you very little. The improvement on this class comes from two directions — direct glucose-dependent insulin secretion and glucagon suppression, plus the indirect effect of weight loss on insulin sensitivity — and the second continues after the first has plateaued.
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View ResultsClosing the loop on my own question.
Update — I was wrong in the opening post, specifically about the direction. Correcting it here rather than editing it away.
Dr.ObesityMed said:HbA1c reflects roughly three months of average glycaemia weighted toward the most recent weeks, which is why repeating it at six weeks tells you very…
Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.