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ForumsPharmacology & MechanismsStructure-activity relationships of GLP-1 analogs — anyone have experience? Page 5

Structure-activity relationships of GLP-1 analogs — anyone have experience?

sarah_TO Wed, Oct 30, 2024 at 10:31 PM 32 replies 1,968 viewsPage 5 of 7
Dr.PeteFamMed
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Nov 9, 2024 at 6:34 AM#21

Adding the numbers, since they settle part of this. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

37 10hyun_seoul, jim_asheville, matt_MKE and 34 others
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sean_dublin
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Nov 11, 2024 at 6:24 AM#22

Following on from claudia_zurich — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

38 11sean_dublin, hannah_MT, Dr.SportsMedIN and 35 others
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tampaLisa73
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Nov 13, 2024 at 6:13 AM#23
Dr.PeteFamMed said:
One practical note: write down what you did and when, before you need it.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

39 12sarah_nash92, FitDadDave, RunnerRach and 36 others
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pam_columbus
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Nov 15, 2024 at 6:00 AM#24
Dr.PeteFamMed said:
One practical note: write down what you did and when, before you need it.

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

40 13tammy_FL, Dr.LipidDallas, alex_tucson and 37 others
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DanielChem_CHI
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Nov 17, 2024 at 5:46 AM#25
Dr.PeteFamMed said:
One practical note: write down what you did and when, before you need it.

This is exactly what I could not find anywhere else. Adding it to my notes with a link back to this thread.

41 14nick_SD_fit, ben_calgary, patPC_UT and 38 others
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