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ForumsOral GLP-1 AgonistsOral GLP-1 for elderly patients — swallowing and compliance advantages Page 5

Oral GLP-1 for elderly patients — swallowing and compliance advantages

GraceAZ_72 Sat, May 16, 2026 at 5:39 PM 31 replies 967 viewsPage 5 of 7
FDA_TrackerJim
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May 20, 2026 at 5:22 AM#21

Adding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

19 17Dr.Martinez, mike_mod, SarahChen_PharmD and 16 others
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josh_phd_bmore
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May 21, 2026 at 12:44 AM#22

Following on from pat_auckland — and this may be the naive question:

Was that from a primary source or from a summary of one?

Last edited: May 21, 2026 at 2:44 AM
20 18Dr.ObesityLA, NurseKim_ATL, paul_denver and 17 others
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Dr.RaviCardio
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May 21, 2026 at 8:06 PM#23
FDA_TrackerJim said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Pushing back on FDA_TrackerJim here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

21 19mark_tokyo, hans_munich, jason_sac26 and 18 others
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hans_munich
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May 22, 2026 at 3:27 PM#24
FDA_TrackerJim said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

22 20tammy_FL, Dr.LipidDallas, alex_tucson and 19 others
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nick_newbie
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May 23, 2026 at 10:48 AM#25
FDA_TrackerJim said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Bookmarking. The distinction being drawn above is the one nobody else makes.

23 21wanda_boise, NurseAsh_DET, BenResearch_OR and 20 others
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