Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
One thing that is still open after Dr.RenalNash’s answer:
How would you tell the difference between that and the alternative explanation?
sean_dublin said:The mechanism and the magnitude are separate questions.
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.
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Browse GL Biochemsean_dublin said:The mechanism and the magnitude are separate questions.
True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Report rather than reply if it drifts again.