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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOff-TopicShowed my before photo to my hairdresser and she gasped — my results so far Page 4

Showed my before photo to my hairdresser and she gasped — my results so far

tyler_CSCS Wed, Sep 10, 2025 at 11:12 PM 26 replies 1,360 viewsPage 4 of 6
paige_pharma
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Sep 19, 2025 at 6:27 AM#16
GenomicsKate said:
Central vs peripheral GLP-1R signaling in food noise: elegant studies using brain-penetrant vs peripherally-restricted GLP-1 agonists show that ~80%…

Adding a me-too, because a thread of one person's experience is not much use. Nothing to add that would improve it.

16 14rachel_ABQ, traveltech_sara, AttorneyGrant and 13 others
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SaraMom3
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Sep 20, 2025 at 2:23 AM#17

A narrower follow-up, since the general answer is now clear:

Was that from a primary source or from a summary of one?

17 15ChrisMacros, KetoKyle, CanadaChris and 14 others
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sean_dublin
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Sep 20, 2025 at 10:18 PM#18
Dr.PeteFamMed said:
If you are going to change something, change one thing and give it long enough to express itself.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

18 16gary_naperville, sean_dublin, hannah_MT and 15 others
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SandraNC_45
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Sep 21, 2025 at 6:13 PM#19
Dr.PeteFamMed said:
If you are going to change something, change one thing and give it long enough to express itself.

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

19 17mike_mealprep, NicoleRaleigh, james_edin and 16 others
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mike_mod
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Sep 22, 2025 at 2:08 PM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Tagging this one for the weekly digest.

41 14PurityPaulOR, MaxMetOK, MounjBrad and 38 others
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