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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesGot off metformin for the first time in 8 years - crying happy tears — looking for input Page 5

Got off metformin for the first time in 8 years - crying happy tears — looking for input

ricardo_MIA Fri, Jan 31, 2025 at 9:41 PM 39 replies 1,834 viewsPage 5 of 8
TrialTracker_MD
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Feb 3, 2025 at 9:48 AM#21
LabKate said:
Keep the original post as written when you update it, and add the correction underneath.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

Last edited: Feb 3, 2025 at 2:48 PM
20 18Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 17 others
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LarryQC_SD
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San Diego, CA
Feb 3, 2025 at 5:22 PM#22
LabKate said:
Keep the original post as written when you update it, and add the correction underneath.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Sending this to two other people who asked me the same thing last week.

21 19paul_denver, TinaHashiRN, robert_kc and 18 others
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sarah_TO
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Toronto, CA
Feb 4, 2025 at 12:55 AM#23

From the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

22 20GraceAZ_72, carl_compliance, DanielChem_CHI and 19 others
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EndoResFellow
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Feb 4, 2025 at 8:28 AM#24
sarah_TO said:
The mechanism and the magnitude are separate questions.

Can confirm. Same sequence, different timescale.

23 21NurseKim_ATL, paul_denver, TinaHashiRN and 20 others
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Dr.SurgeonPGH
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Feb 4, 2025 at 4:01 PM#25
sarah_TO said:
The mechanism and the magnitude are separate questions.

There is a second half to this that has not been said yet. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

24 22B12Beth, RickReta_CO, PharmHunterJen and 21 others
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