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ForumsOral GLP-1 AgonistsHas anyone dealt with attain-2: orforglipron in t2dm? Page 4

Has anyone dealt with attain-2: orforglipron in t2dm?

LipidDoc_ATL Thu, Feb 19, 2026 at 5:55 AM 25 replies 1,000 viewsPage 4 of 5
hannah_MT
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Feb 23, 2026 at 7:56 PM#16
Dr.LeslieOBGYN said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

This matches mine closely enough to be worth saying so out loud. The detail I would add is minor and it is already implied above.

26 1nick_newbie, DadBodDave, AmyNC_wife and 23 others
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JakeBK_lifts
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Feb 24, 2026 at 6:22 AM#17

Following on from NurseKim_ATL — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

Last edited: Feb 24, 2026 at 8:22 AM
25 0JennaRN, LabKate, kate.chem and 22 others
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bbq_ray_KC
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Feb 24, 2026 at 4:48 PM#18
VendorMark said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

This is where I part company with the consensus forming above. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

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mike_nyc
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Feb 25, 2026 at 3:14 AM#19
VendorMark said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

Last edited: Feb 25, 2026 at 7:14 AM
23 23pete_RVA, CarlaRPh_TPA, steph_laguna and 20 others
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Admin
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Feb 25, 2026 at 1:40 PM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.

Last edited: Feb 25, 2026 at 5:40 PM
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