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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsHas anyone dealt with how far away are we really from an oral option? Page 4

Has anyone dealt with how far away are we really from an oral option?

emily_PDX Sun, Jan 4, 2026 at 9:17 AM 17 replies 969 viewsPage 4 of 4
RunnerRach
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Jan 8, 2026 at 7:24 PM#16
Dr.PulmRoch said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Mine went the same way, slower.

10 10BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 7 others
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Dr.GutHealth
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Jan 9, 2026 at 5:55 AM#17

Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Last edited: Jan 9, 2026 at 10:55 AM
9 9tyler_CSCS, VanRx_Mike, steve_okc and 6 others
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Dr.LeslieOBGYN
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Jan 9, 2026 at 4:26 PM#18
Dr.GutHealth said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

This matches mine closely enough to be worth saying so out loud.

Last edited: Jan 9, 2026 at 10:26 PM
8 8james_edin, FranDenver, Dr.BariatricHTX and 5 others
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andrew_nyc
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Jan 10, 2026 at 2:57 AM#19
Dr.GutHealth said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

There is a second half to this that has not been said yet. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

7 7julia.endo, JessicaM_2024, TomFromTexas and 4 others
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Admin
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Jan 10, 2026 at 1:29 PM#20

Moderator note: the sourcing question belongs in the vendor section and has been split out. Tagging this one for the weekly digest.

35 10PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 32 others
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