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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsIs oral sema actually as effective as the injection version? — 12 month update Page 5

Is oral sema actually as effective as the injection version? — 12 month update

tommy_boulder Tue, Dec 16, 2025 at 3:17 AM 35 replies 1,548 viewsPage 5 of 7
BiostatsBrad
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Dec 24, 2025 at 7:00 PM#21

Adding the numbers, since they settle part of this. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

33 8LindaRN_retired, tommy_boulder, hyun_seoul and 30 others
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NauseaFreeNow
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Indiana
Dec 27, 2025 at 3:13 PM#22

Following on from Dr.BariatricHTX — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

32 7maya_sedona, stefan_berlin, Dr.EM_Chicago and 29 others
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Dr.GutHealth
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Dec 30, 2025 at 11:28 AM#23
BiostatsBrad said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Pushing back on BiostatsBrad here. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

31 6jennifer_SEA, tyler_CSCS, VanRx_Mike and 28 others
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tyler_CSCS
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Jun 2024
Phoenix, AZ
Jan 2, 2026 at 7:44 AM#24
BiostatsBrad said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

30 5amy_econ_NJ, bbq_ray_KC, oliver_london and 27 others
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RunnerRach
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Aug 2024
Boston, MA
Jan 5, 2026 at 4:02 AM#25
BiostatsBrad said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Saving this. It is the first explanation that did not require me to already understand it. Adding it to my notes with a link back to this thread.

29 4tyler_CSCS, VanRx_Mike, steve_okc and 26 others
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