A narrower follow-up, since the general answer is now clear:
How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?
NicoleRaleigh said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.
NicoleRaleigh said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
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Browse GL BiochemNicoleRaleigh said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.
Closing the loop on my own question.
Following this thread I went back and re-read the extension data properly. The point about trough rather than peak explains the pattern I was seeing on day six, which I had been blaming on the vial.