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ForumsOral GLP-1 AgonistsOral vs injectable GLP-1: bioavailability and efficacy comparison — anyone have experience? Page 4

Oral vs injectable GLP-1: bioavailability and efficacy comparison — anyone have experience?

stefan_berlin Tue, Nov 18, 2025 at 5:28 PM 45 replies 2,165 viewsPage 4 of 9
Dr.EndoIndy
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Nov 21, 2025 at 2:51 PM#16

From the other side of the consultation, briefly. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Last edited: Nov 21, 2025 at 5:51 PM
42 17mia_MS2, LeilaHI, marcus_mpls and 39 others
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tom_AK
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Nov 22, 2025 at 1:25 AM#17

A narrower follow-up, since the general answer is now clear:

How long did you give it before you decided it was working?

41 16VanRx_Mike, steve_okc, dave_SLC and 38 others
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LipidDoc_ATL
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Nov 22, 2025 at 11:59 AM#18
Dr.EndoIndy said:
It is worth asking what the claim would look like if it were false.

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

Last edited: Nov 22, 2025 at 4:59 PM
40 15AttorneyGrant, DebRD_ATL, KristenIndy and 37 others
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VendorMark
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Nov 22, 2025 at 10:33 PM#19
Dr.EndoIndy said:
It is worth asking what the claim would look like if it were false.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

Ask again with the specifics and you will get a better answer than this one.

Last edited: Nov 23, 2025 at 12:33 AM
39 14Dr.PeteFamMed, claudia_zurich, nancy_portland and 36 others
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Admin
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Nov 23, 2025 at 9:07 AM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. No action needed from anybody.

17 17PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 14 others
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