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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralPartner jealousy after weight loss — how to handle relationship friction

Partner jealousy after weight loss — how to handle relationship friction

AmyNC_wife Tue, May 19, 2026 at 4:41 AM 28 replies 552 viewsPage 1 of 6
AmyNC_wife
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May 19, 2026 at 4:41 AM#1

My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer have my main coping mechanism.

The narrow version of the question is how people separated a drug effect from the ordinary consequences of a large deficit and disrupted sleep, because I cannot.

Happy to be told the question itself is wrong.

28 23JessicaM_2024, TomFromTexas, mike.trainer_LA and 25 others
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Dr.GastroMayo
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May 19, 2026 at 5:19 AM#2
AmyNC_wife said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

I have a history of binge eating disorder. My psychiatrist, therapist, and prescribing doctor all collaborate on my care. The GLP-1 agonist has actually been therapeutic — it removes the biological urgency of binge impulses without relying on restriction.

This is NOT appropriate for all ED patients. Anorexia, bulimia, and restrictive EDs require different approaches. But for BED specifically, the evidence and my personal experience are positive. Always involve your mental health team.

27 22VendorMark, COA_Karl, MikeFit_NJ and 24 others
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amy_econ_NJ
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May 19, 2026 at 5:57 AM#3
Dr.GastroMayo said:
Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

Body image adjustment with mental health: I've lost 88 lbs but when I look in the mirror, I still see my old self sometimes. "Phantom fat" is a real phenomenon.

My therapist specializes in body image issues with weight loss patients. She says it can take 12-18 months for your brain's body map to update. In the meantime: take progress photos (your eyes lie but cameras don't), try on old clothes, and be patient with yourself.

Last edited: May 19, 2026 at 8:57 AM
26 21sean_dublin, hannah_MT, Dr.SportsMedIN and 23 others
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Dr.LeslieOBGYN
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May 19, 2026 at 6:35 AM#4
AmyNC_wife said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

This matches mine closely enough to be worth saying so out loud. Posting only so the count is not one.

Last edited: May 19, 2026 at 12:35 PM
25 20NicoleRaleigh, james_edin, FranDenver and 22 others
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PharmacoVig_BOS
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May 19, 2026 at 10:06 AM#5

Adding the clinical framing, because it changes how the question reads.

AmyNC_wife said:
...mental health should only be used alongside therapy...

I'd say therapy should be AVAILABLE to all GLP-1 patients, but requiring it as a precondition for treatment would create an access barrier.

Not everyone can afford therapy. Not everyone needs it. Some people do just fine with medication + lifestyle changes. But for those with emotional eating, body image issues, or disordered eating history, therapy is extremely valuable.

My recommendation: make mental health screening part of the initial assessment, offer therapy as a recommended adjunct, but don't gatekeep medication access behind it.

24 19LabKate, kate.chem, DataDave and 21 others
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