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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsIs oral sema actually as effective as the injection version? — my results so far Page 3

Is oral sema actually as effective as the injection version? — my results so far

NurseAsh_DET Tue, May 6, 2025 at 11:52 AM 14 replies 1,585 viewsPage 3 of 3
PurityPaulOR
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May 6, 2025 at 6:29 PM#11
pat_auckland said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

Last edited: May 6, 2025 at 9:29 PM
5 3Dr.LeslieOBGYN, MikeNYC_runner and 2 others
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nick_newbie
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May 6, 2025 at 8:34 PM#12
SurmountFan_IN said:
Worth adding that the tablet is taken daily, so a missed dose costs far less than a missed weekly injection.

Bookmarking. The distinction being drawn above is the one nobody else makes. Printing the relevant bit and taking it with me.

Last edited: May 6, 2025 at 11:34 PM
6 4dan_philly, MeganSA_TX, LarryQC_SD and 3 others
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CanadaChris
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May 6, 2025 at 10:39 PM#13
pat_auckland said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

7 5maya_sedona, stefan_berlin, Dr.EM_Chicago and 4 others
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VendorMark
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May 7, 2025 at 12:44 AM#14

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Last edited: May 7, 2025 at 2:44 AM
8 6Dr.PeteFamMed, claudia_zurich, nancy_portland and 5 others
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Admin
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May 7, 2025 at 2:49 AM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

9 7PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 6 others
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