paige_pharma said:

The pharmacokinetics explain nearly every practical question asked here.

This answered a question I did not know how to ask. Taking it to my next appointment.

Clinical perspective, offered as context rather than as advice. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

Correct me if the detail matters more than I have assumed.

Dr.RenalNash said:

Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

I read this differently from Dr.RenalNash, on substance rather than tone. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

Adding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. No action needed from anybody.