PeptideChemSF said:

Freezing is the one to avoid, and freeze-thaw more so.

Storage question about storage and cold: my pen was left out of the fridge for 8 hours. Is it still good?

Per the manufacturer, both Ozempic and Wegovy pens can be stored at room temp (up to 86°F) for up to 28 days after first use. So yes, it should be fine as long as it wasn't exposed to extreme heat.

PeptideChemSF said:

Freezing is the one to avoid, and freeze-thaw more so.

Pushing back on PeptideChemSF here. The distinction that matters is unopened versus in use. Unopened vials are stable refrigerated for their labelled shelf life and tolerate a limited excursion to room temperature. Once reconstituted, the clock is much shorter and is set by the preservative rather than by the peptide — bacteriostatic water's benzyl alcohol is what buys you multiple draws over weeks. Sterile water has no preservative and turns a multi-dose vial into a single-use one.

NurseKim_ATL said:

The distinction that matters is unopened versus in use.

Storage best practices for compounded storage and cold:

• Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months
• Reconstituted vials: refrigerate, use within 28 days
• Pre-filled pens: refrigerate until first use, then room temp OK for 28 days
• Never freeze reconstituted peptides — ice crystals damage the protein
• Protect from light — store in original box or wrap in foil

When in doubt, refrigerate. Temperature abuse is the #1 cause of reduced potency in compounded peptides.

amsterdam_pete said:

Storage question about storage and cold: my pen was left out of the fridge for 8 hours.

Second this. Posting only so the count is not one.