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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsDanuglipron dose optimization — looking for input Page 3

Danuglipron dose optimization — looking for input

bbq_ray_KC Thu, Jan 9, 2025 at 9:03 AM 12 replies 1,816 viewsPage 3 of 3
MariaRD
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Jan 12, 2025 at 1:52 AM#11
PharmD_Rodriguez said:
The OASIS programme put 50mg oral in the same territory as 2.4mg injectable — around 15% mean weight loss — but it needed a dose 20 times larger to…

Genuinely useful, thank you. I had the facts and not the framework.

22 20Dr.NutriCornell, pam_stl, wei_SG and 19 others
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NurseAsh_DET
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Jan 12, 2025 at 5:46 PM#12

Clinical perspective, offered as context rather than as advice. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

Last edited: Jan 12, 2025 at 11:46 PM
23 21ricardo_MIA, BrianDallas92, labquiet_amy and 20 others
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Dr.SleepRoch
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Jan 13, 2025 at 9:39 AM#13
hyun_seoul said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

24 22Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 21 others
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bri_stats
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Jan 14, 2025 at 1:32 AM#14

One concrete data point for the thread. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

25 23JessicaM_2024, TomFromTexas, mike.trainer_LA and 22 others
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mike_mod
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Jan 14, 2025 at 5:25 PM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Carry on.

26 24PurityPaulOR, MaxMetOK, MounjBrad and 23 others
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