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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsCost projections for oral non-peptide GLP-1 agonists — what worked for you? Page 3

Cost projections for oral non-peptide GLP-1 agonists — what worked for you?

LeilaHI Sun, Nov 24, 2024 at 1:21 AM 18 replies 1,817 viewsPage 3 of 4
Dr.GastroMayo
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Nov 29, 2024 at 7:36 PM#11
DeniseRN_TPA said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

50 23mike_nyc, VendorMark, COA_Karl and 47 others
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laura_annarbor
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Nov 30, 2024 at 2:56 PM#12
lisa_labSD said:
Orforglipron is a small molecule rather than a peptide, which is the whole point: no SNAC absorption enhancer, no fasting window, no cold chain, and…

Saving this. It is the first explanation that did not require me to already understand it. Printing the relevant bit and taking it with me.

1 24emily_PDX
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HealthEcon_DC
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Dec 1, 2024 at 10:16 AM#13
DeniseRN_TPA said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

I read this differently from DeniseRN_TPA, on substance rather than tone. The affordability discussion here usually stops at individual tactics. At list price this class is out of reach for most of the people who would benefit, and no amount of appeal strategy changes that — it is a pricing problem wearing a paperwork costume.

2 0KevinCompounds, TirzTom
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bri_stats
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Dec 2, 2024 at 5:36 AM#14

Adding the numbers, since they settle part of this. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

Last edited: Dec 2, 2024 at 9:36 AM
3 1JessicaM_2024, TomFromTexas, mike.trainer_LA
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mike_mod
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Dec 3, 2024 at 12:55 AM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. No action needed from anybody.

4 2PurityPaulOR, MaxMetOK, MounjBrad and 1 other
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