PeptideChemSF said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.
SkepticalSean said:Orforglipron is a small molecule rather than a peptide, which is the whole point: no SNAC absorption enhancer, no fasting window, no cold chain, and…
Saving this. It is the first explanation that did not require me to already understand it.
PeptideChemSF said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.
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Shop Reference StandardsAdding the numbers, since they settle part of this. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.
Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Tagging this one for the weekly digest.