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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareI just want to eat pizza again is that too much to ask Page 6

I just want to eat pizza again is that too much to ask

TomFromTexas Fri, Jan 9, 2026 at 4:22 PM 31 replies 1,064 viewsPage 6 of 7
NauseaFreeNow
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Jan 18, 2026 at 7:48 AM#26
Dr.PathRoch said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Pushing back on Dr.PathRoch here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

3 3stefan_berlin, Dr.EM_Chicago, pete_RVA
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Dr.KarenChen
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Jan 19, 2026 at 8:17 AM#27
Dr.PathRoch said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

2 2JessicaM_2024, TomFromTexas
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FDA_TrackerJim
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Jan 20, 2026 at 8:45 AM#28
Dr.PathRoch said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

This is exactly what I could not find anywhere else. Taking it to my next appointment.

Last edited: Jan 20, 2026 at 11:45 AM
1 1MikeNYC_runner
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DeniseRN_TPA
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Jan 21, 2026 at 9:13 AM#29

Adding the clinical framing, because it changes how the question reads. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

50 0LindaRN_retired, tommy_boulder, hyun_seoul and 47 others
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TomFromTexas
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Jan 22, 2026 at 9:40 AM#30

Closing the loop on my own question.

Follow-up: I read the paper rather than the summary and the qualifier I was missing was in the second paragraph of the results.

28 3BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 25 others
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