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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralGrief over lost years — 6 month update Page 3

Grief over lost years — 6 month update

mel_PDX Wed, Sep 10, 2025 at 10:17 PM 20 replies 1,600 viewsPage 3 of 4
raj_cambridge
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Jun 2024
Cambridge, MA
Sep 12, 2025 at 7:31 AM#11
paige_pharma said:
Before/after narrative for mental health — one year in: Before (297 lbs): Winded climbing stairs, chronic back pain, pre-diabetic, on 3 medications,…

That reframing is the part I needed. Printing the relevant bit and taking it with me.

43 18SleepFixSam, PurityPaulOR, MaxMetOK and 40 others
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NurseKim_ATL
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Feb 2024
Atlanta, GA
Sep 12, 2025 at 9:50 PM#12

Clinical perspective, offered as context rather than as advice.

Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

I have a history of binge eating disorder. My psychiatrist, therapist, and prescribing doctor all collaborate on my care. The GLP-1 agonist has actually been therapeutic — it removes the biological urgency of binge impulses without relying on restriction.

This is NOT appropriate for all ED patients. Anorexia, bulimia, and restrictive EDs require different approaches. But for BED specifically, the evidence and my personal experience are positive. Always involve your mental health team.

42 17raj_cambridge, ingrid_STO, pete_nash and 39 others
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Dr.KarenChen
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Sep 13, 2025 at 12:09 PM#13
NurseAsh_DET said:
When to call your doctor about mental health side effects — a reference I wish I'd had: Call immediately: Severe abdominal pain (could be…

Mood changes on mental health: I want to be transparent — I went through a rough patch emotionally around month 3. Not depression exactly, but a weird flatness. Food was my main coping mechanism and without that, I had to develop new ones.

Therapy has been essential. I'd strongly recommend anyone starting GLP-1 therapy also invest in mental health support. The physical transformation is only half the journey.

41 16TomFromTexas, mike.trainer_LA, sarah_nash92 and 38 others
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PeptideSynthNJ
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Aug 2024
Princeton, NJ
Sep 14, 2025 at 2:28 AM#14
mel_PDX said:
The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.

Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me. Change — even positive change — is stressful. I was anxious about regaining weight.

This is more common than people admit. A therapist who specializes in weight management has been invaluable. Don't neglect the mental health side of this journey.

40 15MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 37 others
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Admin
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Sep 14, 2025 at 4:47 PM#15

Moderator note: a couple of off-topic posts removed.

39 14PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 36 others
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