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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareIs there a ceiling effect for GLP-1-mediated weight loss? — my results so far Page 4

Is there a ceiling effect for GLP-1-mediated weight loss? — my results so far

raj_cambridge Mon, Dec 15, 2025 at 6:20 AM 33 replies 1,411 viewsPage 4 of 7
VendorMark
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Dec 17, 2025 at 4:24 PM#16

From the other side of the consultation, briefly. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

6 6DebRD_ATL, KristenIndy, MarkLI_maint and 3 others
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JenPlateau
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Dec 18, 2025 at 1:00 AM#17
PeptideSynthNJ said:
Say what you would expect to see if you were wrong, before you look.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

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DerekSJ_a1c
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Dec 18, 2025 at 9:36 AM#18
PeptideSynthNJ said:
Say what you would expect to see if you were wrong, before you look.

Thank you — that is the clearest version of this I have read, and I have read a lot of them.

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PeptideChemSF
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Dec 18, 2025 at 6:12 PM#19

From the other side of the consultation, briefly. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

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mike_mod
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Dec 19, 2025 at 2:48 AM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Report rather than reply if it drifts again.

Last edited: Dec 19, 2025 at 4:48 AM
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