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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralRelationship changes after weight loss — my results so far Page 2

Relationship changes after weight loss — my results so far

Dr.Martinez Sat, Aug 16, 2025 at 4:57 PM 42 replies 1,822 viewsPage 2 of 9
LipidDoc_ATL
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Aug 17, 2025 at 11:27 AM#6
mike.trainer_LA said:
Positive side effects of mental health that surprised me: Clearer skin — inflammation reduction improved my rosacea Better sleep — weight loss…

This is where I part company with the consensus forming above. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.

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Dr.NateNeph
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Aug 17, 2025 at 6:48 PM#7
Dr.Martinez said:
The weight came off and the harder part started, which is not what any of the material I read had prepared me for.
Dr.Martinez said:
...mental health should only be used alongside therapy...

I'd say therapy should be AVAILABLE to all GLP-1 patients, but requiring it as a precondition for treatment would create an access barrier.

Not everyone can afford therapy. Not everyone needs it. Some people do just fine with medication + lifestyle changes. But for those with emotional eating, body image issues, or disordered eating history, therapy is extremely valuable.

My recommendation: make mental health screening part of the initial assessment, offer therapy as a recommended adjunct, but don't gatekeep medication access behind it.

Last edited: Aug 17, 2025 at 8:48 PM
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BariatricNurseD
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Aug 18, 2025 at 2:09 AM#8
LipidDoc_ATL said:
I would be careful about how confidently the flatness reports get attributed.

Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

I have a history of binge eating disorder. My psychiatrist, therapist, and prescribing doctor all collaborate on my care. The GLP-1 agonist has actually been therapeutic — it removes the biological urgency of binge impulses without relying on restriction.

This is NOT appropriate for all ED patients. Anorexia, bulimia, and restrictive EDs require different approaches. But for BED specifically, the evidence and my personal experience are positive. Always involve your mental health team.

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hyun_seoul
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Aug 18, 2025 at 9:30 AM#9

One thing that is still open after jason_sac26’s answer:

How long did you give it before you decided it was working?

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Dr.Martinez
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Aug 19, 2025 at 8:45 PM#10

Closing the loop on my own question.

Follow-up — I put something in the gap where food used to be rather than waiting for the gap to close on its own. That was the part nobody told me.

Last edited: Aug 20, 2025 at 1:45 AM
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