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ForumsCompounding & FormulationHas anyone dealt with peptide oxidation and deamidation? Page 5

Has anyone dealt with peptide oxidation and deamidation?

ZaraB_AL Sat, Jan 10, 2026 at 12:20 PM 28 replies 1,096 viewsPage 5 of 6
anders_CPH
Senior Member
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Feb 2024
Copenhagen, DK
Jan 20, 2026 at 7:32 AM#21
MASHdoc_SA said:
503A vs 503B compounding pharmacies for compounded supply — this distinction matters enormously: Feature 503A 503B Regulation State Board of Pharmacy…

Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on the FDA shortage list. If/when the shortage resolves, the legal landscape may change.

Stay informed. The FDA shortage list is updated regularly. Current status as of my last check: semaglutide shortage ongoing, tirzepatide partially resolved. This directly impacts compounding availability.

33 8CryptoCarl, MariaRD, AussieAnna and 30 others
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SkepticalSean
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345
Jan 2025
Maine
Jan 23, 2026 at 12:53 PM#22

Following on from MASHdoc_SA — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

32 7paige_pharma, emma_london, tammy_FL and 29 others
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tammy_FL
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Nov 2024
Tampa, FL
Jan 26, 2026 at 6:15 PM#23
anders_CPH said:
Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on…

Compounded has been just as effective for me. If compounded supply is the concern, the COA from my 503B pharmacy shows 99.1% purity. Verified by Janoshik.

31 6kevin_tulsa, Dr.PainCLE, mike_mealprep and 28 others
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JenMemphis
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Jan 2025
Memphis, TN
Jan 29, 2026 at 11:39 PM#24
anders_CPH said:
Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on…

Price comparison for compounded supply across sources I've used:

SourceMonthly CostTypePurity Verified
Brand (Ozempic)$1016FDA-approvedN/A (pharma)
503B Compounding$146cGMP compoundedYes (in-house)
503A Compounding$126Patient-specificVaries
Research peptide$56Not for human useOften Janoshik

I use the 503B option — best balance of quality, cost, and legality. The brand price is insane but insurance can help if you qualify.

30 5wanda_boise, NurseAsh_DET, BenResearch_OR and 27 others
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InsuranceTom
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Mar 2024
Connecticut
Feb 2, 2026 at 5:05 AM#25
anders_CPH said:
Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on…

Thank you for spelling out the reasoning rather than just the conclusion.

Last edited: Feb 2, 2026 at 10:05 AM
29 4jim_asheville, matt_MKE, Dr.ReproEndo and 26 others
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