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ForumsPublic SquareCost-effectiveness analysis: GLP-1 agonists vs bariatric surgery (ICER 2026) — looking for input

Cost-effectiveness analysis: GLP-1 agonists vs bariatric surgery (ICER 2026) — looking for input

SkepticalSean Sat, Sep 27, 2025 at 2:23 AM 14 replies 1,388 viewsPage 1 of 3
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SkepticalSean
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Maine
Sep 27, 2025 at 2:23 AM#1

Elective procedure in five weeks and two different sets of instructions from two different departments about when to stop.

The narrow version of the question is how long before a procedure people were told to hold, and whether the interval differs between the weekly and daily agents.

Happy to be told the question itself is wrong.

33 3DerekSJ_a1c, paige_pharma, emma_london and 30 others
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Dr.NateNeph
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Sep 27, 2025 at 4:34 AM#2

Answering the narrow version, because the broad one does not have a single answer. Denials are usually procedural rather than clinical, and the order that works reflects that. Get the denial reason in writing, because it names the criterion you failed. Then supply the documentation that criterion asks for — usually documented BMI with a comorbidity, or a failed prior therapy. Then appeal, and ask for a peer-to-peer review, because a prescriber talking to a reviewing clinician resolves a large fraction of denials that written appeals do not. Manufacturer copay assistance is separate and applies mainly to commercial insurance, and patient assistance programmes are means-tested rather than a discount.

32 2NauseaFreeNow, SteveThurs, B12Beth and 29 others
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ben_calgary
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Oct 2024
Calgary, CA
Sep 27, 2025 at 6:45 AM#3
Dr.NateNeph said:
Denials are usually procedural rather than clinical, and the order that works reflects that.

Agreed, and coverage criteria are plan-specific rather than insurer-specific. Two people with the same insurer and different employers have different rules, which is why "my insurer covers it" is not transferable information.

Last edited: Sep 27, 2025 at 12:45 PM
31 1ZaraB_AL, JakeSmashed95, NauseaFreeNow and 28 others
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josh_phd_bmore
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Baltimore, MD
Sep 27, 2025 at 8:56 AM#4
SkepticalSean said:
Elective procedure in five weeks and two different sets of instructions from two different departments about when to stop.

Mine went the same way, slower. The detail I would add is minor and it is already implied above.

Last edited: Sep 27, 2025 at 10:56 AM
30 0KarenAZ_mom, zoe_NC, Dr.ObesityLA and 27 others
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Dr.PainCLE
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Cleveland, OH
Sep 27, 2025 at 9:55 PM#5

From the other side of the consultation, briefly.

Important PSA about surgery and anaesthesia and anesthesia: GLP-1 agonists delay gastric emptying, which increases aspiration risk during procedures requiring sedation or general anesthesia.

Current ASA guidelines recommend stopping GLP-1 agonists 1 week before scheduled procedures. ALWAYS tell your surgical team you're on this medication. Don't let this get overlooked.

29 24amy_econ_NJ, bbq_ray_KC, oliver_london and 26 others
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