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ForumsPublic SquareAdolescent obesity: AAP guidelines and GLP-1 use in minors — what worked for you? Page 3

Adolescent obesity: AAP guidelines and GLP-1 use in minors — what worked for you?

RunnerRach Mon, Aug 25, 2025 at 5:11 AM 12 replies 1,265 viewsPage 3 of 3
FDA_TrackerJim
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Aug 30, 2025 at 9:33 PM#11
Dr.PeteFamMed said:
Forest plot interpretation for the the trial evidence meta-analysis: when reading the pooled estimate, pay attention to: Point estimate (HR/RR/OR) —…

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

Last edited: Aug 31, 2025 at 12:33 AM
27 2Dr.Martinez, mike_mod, SarahChen_PharmD and 24 others
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CryptoCarl
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Aug 31, 2025 at 2:28 PM#12
kim_atl_prep said:
Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.

That reframing is the part I needed. Printing the relevant bit and taking it with me.

26 1MariaRD, AussieAnna, BethLabQueen and 23 others
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LeilaHI
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Sep 1, 2025 at 7:24 AM#13
Dr.PeteFamMed said:
Forest plot interpretation for the the trial evidence meta-analysis: when reading the pooled estimate, pay attention to: Point estimate (HR/RR/OR) —…

I read this differently from Dr.PeteFamMed, on substance rather than tone. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

Last edited: Sep 1, 2025 at 12:24 PM
25 0mike_nyc, VendorMark, COA_Karl and 22 others
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anders_CPH
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Sep 2, 2025 at 12:20 AM#14

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

24 24BethLabQueen, ChrisMacros, KetoKyle and 21 others
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mike_mod
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Sep 2, 2025 at 5:16 PM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. No action needed from anybody.

23 23PurityPaulOR, MaxMetOK, MounjBrad and 20 others
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