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ForumsPublic SquareCompounded sema shortage — my results so far Page 6

Compounded sema shortage — my results so far

mark_tokyo Sat, Aug 16, 2025 at 4:25 PM 32 replies 1,406 viewsPage 6 of 7
SaraMom3
Member
456
2,345
Aug 2024
Ohio
Aug 20, 2025 at 1:07 AM#26
wendy_avl said:
Vendor communication red flags for compounded supply: Won't provide COA before purchase — walk away Claims "100% pure" without analytical data —…

Compounding pharmacy red flag checklist for compounded supply — if ANY of these apply, find a different source:

  1. No verifiable physical address
  2. No pharmacist available for consultation
  3. COA not available or clearly template/fake
  4. Prices dramatically below market ($30-40/month = suspicious)
  5. No prescription required
  6. Ships without cold pack or temperature control
  7. No batch/lot numbers on product labeling
  8. Pushes "research use only" products for human injection

Your health depends on product quality. Don't cut corners on source verification.

46 21BethLabQueen, ChrisMacros, KetoKyle and 43 others
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JessicaM_2024
Member
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3,456
Mar 2024
Portland, OR
Aug 20, 2025 at 9:10 AM#27
wendy_avl said:
Vendor communication red flags for compounded supply: Won't provide COA before purchase — walk away Claims "100% pure" without analytical data —…

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

45 20NicoleRaleigh, james_edin, FranDenver and 42 others
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anders_CPH
Senior Member
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7,234
Feb 2024
Copenhagen, DK
Aug 20, 2025 at 5:13 PM#28

Adding the clinical framing, because it changes how the question reads.

FDA inspection results for compounding pharmacies selling compounded supply: you can look up any 503B facility's FDA inspection history on the FDA website.

Check for: Form 483 observations (violations), warning letters, and recall history. A clean inspection record is a strong indicator of quality. My pharmacy has had 0 Form 483 observations in their last 4 inspections.

This is public information. Use it. Link: fda.gov/inspections-compliance-enforcement-and-criminal-investigations

44 19AussieAnna, BethLabQueen, ChrisMacros and 41 others
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DadBodDave
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187
923
Nov 2024
Ohio
Aug 21, 2025 at 1:16 AM#29
anders_CPH said:
FDA inspection results for compounding pharmacies selling compounded supply: you can look up any 503B facility's FDA inspection history on the FDA…

Same experience, arrived at from the opposite direction. Nothing to add that would improve it.

43 18Dr.GastroMayo, JakeBK_lifts, DerekSJ_a1c and 40 others
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mark_tokyo
Member
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Jun 2024
Tokyo, JP
Aug 21, 2025 at 9:20 AM#30
anders_CPH said:
FDA inspection results for compounding pharmacies selling compounded supply: you can look up any 503B facility's FDA inspection history on the FDA…

Compounding pharmacy customer here with experience relevant to compounded supply.

I've ordered from 2 different compounding pharmacies over the past 2 years. The quality variation is real — purity ranged from 94% to 101% of label claim based on independent Janoshik testing.

My current compounder (a 503B facility) has been consistently 98-101% purity across 10 orders. I pay $141/month vs $1,311 for brand. The savings are substantial and the product is equivalent in my experience.

Re: compounded supply — this applies whether you're using brand or compounded. The clinical principles are the same.

21 21TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 18 others
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