Following on from carl_compliance — and this may be the naive question:
Did your prescriber agree with that reading, and if not what was their objection?
labquiet_amy said:Follow-up: I read the paper rather than the summary and the qualifier I was missing was in the second paragraph of the results.
This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.
labquiet_amy said:Follow-up: I read the paper rather than the summary and the qualifier I was missing was in the second paragraph of the results.
That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.
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View Resultslabquiet_amy said:Follow-up: I read the paper rather than the summary and the qualifier I was missing was in the second paragraph of the results.
Genuinely useful, thank you. I had the facts and not the framework. Taking it to my next appointment.
Adding the clinical framing, because it changes how the question reads. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
Ask again with the specifics and you will get a better answer than this one.