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Evidence-based GLP-1 & peptide discussion since 2023
ForumsTirzepatide (Mounjaro / Zepbound)Tirz + walking = the only combo I needed apparently Page 6

Tirz + walking = the only combo I needed apparently

wanda_boise Thu, Mar 19, 2026 at 10:58 AM 26 replies 834 viewsPage 6 of 6
julia.endo
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May 7, 2026 at 2:40 PM#26
jason_paloalto said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Genuinely useful, thank you. I had the facts and not the framework.

47 20anna.melb_AU, mark_tokyo, hans_munich and 44 others
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DebRD_ATL
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May 14, 2026 at 1:57 AM#27

From the other side of the consultation, briefly. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

48 21RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 45 others
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PharmD_Rodriguez
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May 20, 2026 at 1:11 PM#28
DebRD_ATL said:
It helps to ask what evidence would change your mind before you look at any.

Second this.

49 22robert_kc, dan_philly, MeganSA_TX and 46 others
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PeptideSynthNJ
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May 27, 2026 at 12:20 AM#29
DebRD_ATL said:
It helps to ask what evidence would change your mind before you look at any.

There is a second half to this that has not been said yet. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

That is the short version; the long version is somebody else's post.

50 23MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 47 others
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wanda_boise
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Boise, ID
Jun 2, 2026 at 11:26 AM#30

Reporting back.

For the archive: it took about six weeks rather than the two I expected, and the difference between those two numbers was the whole of my problem.

22 20ben_calgary, patPC_UT, Dr.DermMIA and 19 others
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