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ForumsCompounding & FormulationEndotoxin testing in compounded injectables — looking for input Page 6

Endotoxin testing in compounded injectables — looking for input

rick_sfbay Wed, Sep 10, 2025 at 5:43 PM 35 replies 1,765 viewsPage 6 of 7
jason_paloalto
Member
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890
Nov 2024
Palo Alto, CA
Dec 7, 2025 at 3:11 AM#26
JenPlateau said:
Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on…

Compounding pharmacy licensing verification for compounded supply: before ordering, verify your pharmacy's credentials:

  1. State Board of Pharmacy license — check on your state BOP website
  2. FDA registration (for 503B) — check on fda.gov
  3. DEA registration if handling controlled substances
  4. PCAB accreditation — voluntary but demonstrates commitment to quality
  5. USP <797>/<800> compliance for sterile compounding

This takes 10 minutes of research and could save you from receiving substandard or unsafe medication.

Last edited: Dec 7, 2025 at 8:11 AM
37 10tane_welly, Dr.PathRoch, mona_PHX and 34 others
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NurseKim_ATL
Senior Member
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7,234
Feb 2024
Atlanta, GA
Dec 18, 2025 at 7:38 PM#27

A narrower follow-up, since the general answer is now clear:

What would you measure differently if you were starting again?

Last edited: Dec 19, 2025 at 12:38 AM
38 11raj_cambridge, ingrid_STO, pete_nash and 35 others
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MounjBrad
Member
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890
Oct 2024
Kentucky
Dec 30, 2025 at 11:58 AM#28
jason_paloalto said:
Compounding pharmacy licensing verification for compounded supply: before ordering, verify your pharmacy's credentials: State Board of Pharmacy…

Vendor communication red flags for compounded supply:

  • Won't provide COA before purchase — walk away
  • Claims "100% pure" without analytical data — unrealistic
  • No physical address or phone number — accountability matters
  • Pushes you to buy more than you need — pressure tactics
  • Won't answer questions about their compounding process — transparency is key
  • Payment only via crypto or wire transfer — legitimate pharmacies accept cards

A legitimate compounding pharmacy operates like a healthcare business, not a gray market dealer.

Last edited: Dec 30, 2025 at 4:58 PM
39 12nick_SD_fit, ben_calgary, patPC_UT and 36 others
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Dr.Martinez
Medical Advisor
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28,456
Nov 2023
Boston, MA
Online
Jan 11, 2026 at 4:11 AM#29
jason_paloalto said:
Compounding pharmacy licensing verification for compounded supply: before ordering, verify your pharmacy's credentials: State Board of Pharmacy…

FDA inspection results for compounding pharmacies selling compounded supply: you can look up any 503B facility's FDA inspection history on the FDA website.

Check for: Form 483 observations (violations), warning letters, and recall history. A clean inspection record is a strong indicator of quality. My pharmacy has had 1 Form 483 observations in their last 2 inspections.

This is public information. Use it. Link: fda.gov/inspections-compliance-enforcement-and-criminal-investigations

40 13Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 37 others
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rick_sfbay
Member
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1,234
Jan 2025
San Francisco, CA
Jan 22, 2026 at 8:17 PM#30
MounjBrad said:
Vendor communication red flags for compounded supply: Won't provide COA before purchase — walk away Claims "100% pure" without analytical data —…

For compounded supply users considering compounded for the first time: here's a step-by-step guide:

  1. Get a prescription from your doctor (telehealth counts)
  2. Research 503B compounding pharmacies with good community reviews
  3. Verify their FDA registration and inspection history
  4. Request a COA for your specific compound before ordering
  5. Start with a 1-month supply to test
  6. Consider sending a sample to Janoshik for independent verification
  7. Track your response compared to brand (if you were on it previously)
12 10Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 9 others
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