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ForumsCompounding & FormulationUSP <797> 2023 revision impact on peptide compounding — July 2024 Page 5

USP <797> 2023 revision impact on peptide compounding — July 2024

sean_dublin Sat, Aug 16, 2025 at 12:23 PM 37 replies 1,520 viewsPage 5 of 8
JessicaM_2024
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Portland, OR
Aug 31, 2025 at 7:21 AM#21

One thing that is still open after Dr.ObesityMed’s answer:

Was that from a primary source or from a summary of one?

Last edited: Aug 31, 2025 at 8:21 AM
42 15james_edin, FranDenver, Dr.BariatricHTX and 39 others
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dave_SLC
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Salt Lake City, UT
Sep 5, 2025 at 11:11 PM#22
oliver_london said:
Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on…

Vendor communication red flags for compounded supply:

  • Won't provide COA before purchase — walk away
  • Claims "100% pure" without analytical data — unrealistic
  • No physical address or phone number — accountability matters
  • Pushes you to buy more than you need — pressure tactics
  • Won't answer questions about their compounding process — transparency is key
  • Payment only via crypto or wire transfer — legitimate pharmacies accept cards

A legitimate compounding pharmacy operates like a healthcare business, not a gray market dealer.

43 16NicoleRaleigh, james_edin, FranDenver and 40 others
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carl_compliance
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Nov 2024
Raleigh, NC
Sep 11, 2025 at 3:04 PM#23
oliver_london said:
Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on…

Compounded has been just as effective for me. If compounded supply is the concern, the COA from my 503B pharmacy shows 99.1% purity. Verified by Janoshik.

44 17ricardo_MIA, BrianDallas92, labquiet_amy and 41 others
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TirzTom
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Sep 17, 2025 at 7:00 AM#24
oliver_london said:
Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on…

Genuinely useful, thank you. I had the facts and not the framework. Printing the relevant bit and taking it with me.

45 18SandraNC_45, Dr.EndoIndy, tom_AK and 42 others
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Dr.GastroMayo
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Mayo Clinic, MN
Sep 22, 2025 at 11:00 PM#25

From the other side of the consultation, briefly.

I have been on both brand and compounded, and in the context of compounded supply, my experience has been equivalent with both. The key is finding a reliable 503B pharmacy with independent testing.

46 19InsuranceTom, WendyG_ATL, SaraMom3 and 43 others
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